What is the Difference Between Cannabinoids and Cannabidiol?

As you set out to learn more about cannabidiol (CBD) and its properties, it’s not uncommon to find yourself confused over many of the terms related to the compound. Often times, people have a challenging time understanding how cannabidiol differs from cannabinoids, two commonly used terms that share spelling similarities and are often used interchangeably.

To begin, it’s helpful if you understand that cannabidiol (CBD) is a type of cannabinoid. In fact, it’s one of more than 100 cannabinoids found throughout the stalks, seeds, and flowers of cannabis plants like hemp. From there, let’s dive in a bit deeper to better understand how these two terms differ.

What are Cannabinoids?

 

natural-cannabinoids

 

Cannabinoids are active chemical compounds found naturally in the seeds, stalk and flowers of cannabis plants. Phytocannabinoids, a term used to describe cannabinoids derived from plants, are able to interact with our body’s natural systems because their makeups and behaviors mimic endocannabinoids, which are cannabinoids that are synthesized on demand by our own bodies.

Our bodies are set up to interact with cannabinoids. Both phytocannabinoids and endocannabinoids join with or influence cannabinoid receptors throughout the body to alter the release of neurotransmitters and encourage balance in our systems. Cannabinoids are largely responsible for the natural effects that cannabis oils, such as CBD Hemp oil, have on the body.

Scientists have so far identified over 100 phytocannabinoids found in cannabis plants like hemp. The two most abundant cannabinoids include cannabidiol (CBD) and tetrahydrocannabinol (THC).

The cannabinoid composition of a cannabis plant is wide ranging and varies by strain. Some are higher in CBD and others contain more THC. Hemp is naturally higher in CBD and contains only trace amounts of THC. 

 

What is Cannabidiol?

Cannabidiol2

Cannabidiol, also known as CBD, is among the most abundant of all the cannabinoids. It’s found in all varieties of cannabis, but dominates the makeup of hemp plants.

Thousands of scientific studies suggest that cannabidiol may hold a wide array of potential benefits. CBD has been shown in a patent by the U.S. National Institutes of Health to possess significant and antioxidant and neuroprotective properties, suggesting that it could be beneficial for treating neurological disorders like Alzheimer’s disease or multiple sclerosis. Several studies have found CBD to be effective for reducing, and in some cases eliminating, seizure activity. *

Studies have shown that cannabidiol is a non-psychoactive cannabinoid, unlike THC. Therefore, consuming CBD won’t ever cause a high or temporarily inhibit cognitive functions. This makes CBD an appealing option for children or anyone looking to incorporate the balancing effects of cannabinoids without having to experience the fuzziness of a high.

CBD Hemp Oil is made from hemp that is naturally high in CBD and low in THC. Because hemp contains only trace amounts of the cannabinoid THC, hemp oil products are non-psychoactive.

Now that you know the difference between Cannabinoids and Cannabidiol … Check out these CBD Hemp Oils and Products

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Original Article: https://echoconnection.org/difference-cannabinoids-cannabidiol

 

Can CBD Hemp Oil Help You?
Due to federal regulations, no claims can be made about any specific ailments that may be alleviated or cured with the use of CBD Hemp Oil. However, you can do your own research with the product and see if it helps you.
*These statements have not been evaluated by the Food and Drug Administration. This product/products are not intended to diagnose, treat, cure or prevent any disease.

NEW CTFO CBD HEMP PRODUCTS

All of our NEW CTFO Products will be available 

Friday, 5 October 2018

 

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Wholesale: $99.97 for 500 

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This supercharged Full Spectrum CBD Oil is Hydrophilic, meaning it can be mixed with water. It provides accelerated, increased absorption and potency and acts as an anti-bacterial and probiotic. CBD has been known to support healthy blood sugar levels, promote healthy energy levels, relieve anxiety, aid in digestion, support optimal immune function and the regeneration of healthy cells, and promote a sense of serenity and overall well-being. Perfect for anyone wanting to treat severe health challenges and regain optimal health. Each bottle contains 50 servings of Pure CBD Hemp Oil and 10xPure which can be used twice daily.

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What is AnaGain? Watch this VIDEO

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Step 1: Hair Growth Shampoo with AnaGain

This shampoo is the first step of a 4-step system to increase hair growth. AnaGain stimulates specific signal molecules in the hair to reactivate and promote hair growth. AnaGain combined with 50 mg of CBD per container helps to give your hair the nourishment and stimulation needed to grow fuller and thicker! This product is intended to be used in a 4-step system but can be used separately.

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This conditioner is the second step of a 4-step system to increase hair growth. AnaGain stimulates specific signal molecules in the hair to reactivate and promote hair growth. AnaGain combined with 50 mg of CBD per container helps to give your hair the nourishment and stimulation needed to grow fuller and thicker! This product is intended to be used in a 4-step system but can be used separately.

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Step 3: Hair Growth Leave-In Solution with AnaGain

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This leave-in solution is the third step of a 4-step system to increase hair growth. AnaGain stimulates specific signal molecules in the hair to reactivate and promote hair growth. AnaGain combined with 100 mg of CBD per container helps to give your hair the nourishment and stimulation needed to grow fuller and thicker! This product is intended to be used in a 4-step system but can be used separately.

·      STIMULATES hair growth

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·      NATURAL contributor to fuller and thicker hair

 

Step 4: Hair Growth Moisture Treatment with AnaGain

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This hair mask moisture treatment should be used once or twice weekly but can be used up to five times. This is the final step of the 4-step system to increase hair growth. AnaGain stimulates specific signal molecules in the hair to reactivate and promote hair growth. AnaGain combined with 100 mg of CBD per container helps to give your hair the nourishment and stimulation needed to grow fuller and thicker! After using the moisture treatment, follow with shampoo and conditioner. This product is intended to be used in a 4-step system but can be used separately.

·      STIMULATES hair growth

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·      NATURAL contributor to fuller and thicker hair

 

 

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Massage Oil with Anointing Oil

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CBD Dead Sea Mud Mask with Vulcanus Kaolin – 50 mg CBD

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500 mg CBD Ultimate Deep Healing Pain Cream with Emu Oil

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Our Ultimate Deep Healing Pain Cream with Emu Oil contains 500 mg of CBD oil and helps to deeply penetrate the toughest aches & sores. Natural anti-inflammatory properties from Emu Oil combined with our hemp intensive formula. Apply as needed to problem areas. Great for chronic conditions! Apply to areas experiencing tension or pain. This product can be used as often as necessary.

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AIDS joint ailments and stiffness

 

 

NON – CBD PRODUCTS:

 

Non-CBD Dead Sea Mud Mask with Vulcanus Kaolin

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This face mask helps to cleanse and exfoliate debris and skin cells on the surface of the skin. The Vulcanus Kaolin is a clay mineral which helps to absorb excess oils, leaving your skin feeling clean and rejuvenated.

·      CLEANSES skin

·      EXFOLIATES skin

·      REJUVENATES skin

 

Non-CBD 2.5% Retinol Complex Serum

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Non-CBD Your Majesty Queen of all Creams Moisturizing Cream

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Treat your skin the way it deserves to be treated! This moisturizing cream is packed full of the best ingredients to help your skin feel refreshed, youthful and moisturized. This cream can be used daily to maintain moisture on normal skin, to provide moisture for dry skin or to balance moisture for oily skin. It is great for sensitive skin, dry and cracked skin, provides skin relief for cold weather and provides a protective layer over your skin to protect against the environment. This product can be used on the face or the body twice daily.

·      MOISTURIZES skin

·      COMBATS the aging process

·      Leaves skin feeling REFRESHED

 

On October 5th, they will be available for Ordering. 

Order HERE

 

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Drugs that may Interact with CBD Hemp Oil

CBD and Drug Interactions

 

If you are on one or several medications, you may want to print this out or save the link, to share this information with your doctor for both of you to discuss the best course of action for your health and wellness plan. 

Research has begun to demonstrate that cannabidiol (CBD) has the potential to effectively help a large number of people. CBD interacts with the endocannabinoid system in a way that produces very few unintended side-effects.

While the majority of the vast majority of the science indicates CBD is safe for use and consumption, it does pose a few risks that, if not properly understood, could be dangerous. One of these risks is the inhibition of the cytochrome P450 enzyme system.

What is the Cytochrome P-450 System?

Found within the liver, the cytochrome P450 enzyme system is responsible for metabolizing potentially toxic compounds, including over 60% percent of any drugs you have consumed.

According to Davis’s Drug Guide, this system contains more than 50 enzymes that process and eliminate toxins.

Why Does CYP450 Matter?

In order to determine the appropriate dosages of medications, doctors make calculations using the average amount of time it takes for various drugs and medications to be processed through the cytochrome P450 system.

If only one drug is being processed, and the system is generally healthy, these averages provide accurate dosage information.

However, certain substances have the ability to affect processing times within this system, making drugs metabolize faster or slower than they would on their own.

Similarly, if the cytochrome P450 system is unhealthy due to problems with the liver or other pre-existing conditions, drugs may not metabolize as they should.

Cannabidiol in the Cytochrome P-450 System

Cannabidiol can inhibit the cytochrome P450 system’s ability to metabolize certain drugs, leading to an overall increase in processing times.

Interestingly, CBD is not alone in its effect on drug metabolism. Grapefruit, watercress, St. John’s Wort, and goldenseal all have a similar impact in terms of CYP450 inhibition.

When the CYP450 system is impacted in this way, it leads to higher levels of certain drugs in your system at one time. This can cause unwanted side effects, and sometimes, an overdose.

If you are taking a medication affected by cannabidiol, you should consult your doctor to make sure that it is safe for you to supplement your personal care routine with CBD Hemp. From there, the two of you may consider adjusting the dosage on your medications so that you can use both products safely.  

 

Drugs that Interact with Cannabidiol

Any drug metabolized by CYP450 enzymes could potentially interact with cannabidiol. According to the Indiana University Department of Medicine, drugs known to use the CYP450 system include:

  • Steroids
  • HMG CoA reductase inhibitors
  • Calcium channel blockers
  • Antihistamines
  • Prokinetics
  • HIV antivirals
  • Immune modulators
  • Benzodiazepines
  • Antiarrythmics
  • Antibiotics
  • Anesthetics
  • Antipsychotics
  • Antidepressants
  • Anti-epileptics
  • Beta blockers
  • PPIs
  • NSAIDs
  • Angiotension II blockers
  • Oral hypoglycemic agents
  • Sulfonylureas

 

This list does not include all of the potential medications impacted by cannabidiol. Nor will every medication in the categories contained on this list will cause an interaction. For these reasons, you should consult with a medical professional before supplementing with CBD Hemp products.

There are certain medications, known as “prodrugs,” that need to be metabolized to produce the therapeutic compound. In other words, you ingest an inactive compound and once in the body, it is processed into the active drug. If this processing is dependent on CYP3A4 (part of the larger CYP450 system), then inhibitors can result in too little active drug in the body for the desired therapeutic effect.

Codeine, for example, is a prodrug that is metabolized into morphine which provides the effect.

Vyvanse and Concerta are two other popular pharmaceutical medications for ADHD that fall into this category.

If you are worried that your CYP450 pathway may not be functioning properly, physicians can test the system to ensure that the medications you take are metabolizing as expected.

If you are on one or several medications, you may want to print this out or save the link, to share this information with your doctor for both of you to discuss the best course of action for your health and wellness plan. 

 

Combining Alcohol and CBD Oil

Alcohol and cannabis are both widely consumed in our society and the effects of combining the two are well known.

What is less understood by the general public, is the effects of combining alcohol and the cannabinoid compound CBD.

Alcohol depends on a few different metabolic pathways in the human body, with the primary enzymes involved being:

  • Alcohol dehydrogenase (ADH)
  • Aldehyde dehydrogenase (ALDH)
  • CYP450 (specifically CYP2E1)

In people who only drink socially or occasionally, ADH and ALDH handle the entire workload of metabolizing ethanol. However, when binge drinking (or during chronic consumption of alcohol) CYP450 gets involved to assist the overloaded ADH and ALDH pathways.

Here are some interesting tidbits about alcohol and CBD:

  • The CB1 receptor is a significant player in the reinforcing and motivating attributes of alcohol. [S]
  • Combining alcohol and CBD results in significantly lower blood levels of alcohol. [S]
  • CBD reduces the reinforcement, motivation and relapse for alcohol. [S]
  • CBD protects the liver from damage done by binge-drinking alcohol. [S]
  • CBD prevents against alcohol-induced neurodegeneration. [S]
  • CBD attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury. [S]
  • Cannabinoids have an effect on nearly all enzymes responsible for metabolizing alcohol. [S]
  • CB1 receptor agonists (THC) encourage alcohol consumption, while CB1 receptor antagonists (CBD) decrease it. [S]

Although the pharmacokinetics of alcohol and CBD are not yet well-understood, what we do know is CBD inhibits the CYP450 enzyme system, and this system plays a significant role in alcohol metabolism. Additionally, as found in mice, CBD alters levels of ADH and ALDH to varying degrees.

It is important to be mindful and cautious when mixing CBD and alcohol.

 

 

Original Article:  https://cbdoilreview.org/cbd-cannabidiol/cbd-p-450-enzyme

 

CBD helps with Sleep and Insomnia.

Complications_of_insomnia

Insomnia In The U.S. is still a pressing Public Health Problem.

According to a recent Huffington Post article by Catherine Pearson, “Sleep is a major problem for many Americans, according to a new report that acts as a kind of “state-of-insomnia” in the U.S. The review, published online by the medical journal The Lancet, finds that nearly a quarter of adults are unhappy with their sleep patterns, while up to 10 percent meet the criteria for full-fledged insomnia, putting them at a greater risk for depression, hypertension and diabetes.”

It’s easy to joke about this issue… but it’s no joke. Why do so many of us have trouble falling asleep or sleeping through the night? Some say it’s our stress-filled lifestyles. Some say it’s a by-product of anxiety. Some say we’ve become dependent on alcohol or over-the-counter drugs to help us sleep. The truth is, using these crutches may actually interfere with the deep “REM” sleep that we all need for rest and recuperation.

 

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CTFO’s Sleep Support Oral Spray uses a combination of CBD and Melatonin to help you fall asleep naturally and without drugs or alcohol. Both of these natural ingredients have been shown to relax you and help you fall asleep. Some of our customers even say the CBD drops alone help them fall asleep.

With better quality sleep, we can all have more peaceful nights and better overall health.

Purchase CTFO’s Sleep Support Oral Spray HERE

 

 

Catherine Pearson’s article: https://www.huffingtonpost.com/2012/01/20/insomnia-health-problem-study_n_1217093.html

What’s the Difference between Hemp and Marijuana?

Difference between THC and CBD Hemp Oil

 

As you dig in and learn more about medical marijuana, CBD hemp oil, and more, one of the common questions that come up is “what exactly is the difference between hemp and marijuana?”

Beyond cannabis slang, legal interpretation, and practical use of the plant, the fact of the matter is that few genetic differences exist between hemp and marijuana plants, but in practical terms, the differences are quite significant.

Hemp and marijuana are actually both members of the same plant species, Cannabis sativa L. Cannabis sativa L. can contain a wide spectrum of cannabinoid concentrations, including wide ranging compositions of THC and CBD. Still, there are many practical differences between hemp and marijuana, and clear lines drawn between the two.

In practical use, “hemp” is the term used to describe the food and fiber variety of the cannabis plant, and “marijuana” is cannabis that’s grown to enhance the chemicals that make you feel high or stoned.

Cannabis has both male and female plants. When growing marijuana, male plants are removed and only female plants are cultivated. This is because when cannabis is fertilized, it lowers the concentration of THC–the main chemical that gets you high. Thanks to selective breeding over many years, ideal concentrations of THC in marijuana range from 10% to as much as 30%. This will be important to remember in a moment when we compare marijuana to hemp.

Marijuana is usually grown indoors so that conditions can be monitored very closely. Marijuana is encouraged to become short and bushy and grow lots of flowers. That’s because THC is concentrated mostly in the trichomes — little resin-filled glands — on the flowers of the plant. Although you can find THC throughout cannabis, it is the flowers or “buds” that are harvested for recreational marijuana.

Hemp, on the other hand, is as close as you can get to how cannabis grows naturally. Hemp is grown all over the world for food, oil, and fiber — so, the whole plant can be used, not just the flowers. With the hemp type of cannabis, male and female plants are sown very closely together, allowing for easy wind pollination and easily crowding out weeds. This results in very tall, hardy plants with less branching that look very different from the short, bushy marijuana plants.

Another key difference between hemp and marijuana is that hemp naturally has almost no THC. Its flowers must contain just 0.3% THC — which is 33 times less than the least potent marijuana. Meaning, it’s impossible to get high from hemp, although many people have tried!

Hemp also has more CBD than THC naturally, making it an ideal source of CBD from cannabis and one of the reasons why hemp oil is the preferred source of natural CBD for thousands of people.

 

 

Original Article: https://www.medicalmarijuanainc.com/whats-the-difference-between-hemp-and-marijuana/

 

Epilepsy in Dogs and CBD for Treatment

CB Receptors in your dogs body
For most dogs, epilepsy is a lifelong disease requiring a regimented routine of care and treatment as prescribed by your veterinarian. A canine seizure is the result of abnormal electrical impulses in the brain which lead to sudden but short-term disturbances in your dog’s behavior and physical movements.

Dogs with idiopathic epilepsytypically have their first seizures between the ages of 6 months to 6 years. Though idiopathic epilepsy can occur in any breed, it is considered an inheritable disease in many breeds and in some breeds a genetic basis has been identified. Therefore, dogs diagnosed with idiopathic epilepsy should not be used for breeding.

Commonly affected breeds include:

Labrador retrievers
Golden retrievers
Poodles
Keeshonds
Beagles
German shepherds
Dachshunds
Irish setters
Cocker spaniels

Symptoms
Prolonged seizures lasting more than 5 minutes or two or more consecutive seizures without full recovery are referred to as status epilepticus. This is a true emergency and you should seek immediate veterinary care for you pet. Two or more seizures in 24 hours are referred to as cluster seizures and are an indication for beginning anti-seizure medication.

It may be difficult to watch your pet have a seizure but most are of short duration and cause no permanent harm. Avoid being bitten by keeping your hands away from your pet’s mouth during a seizure. If it can be done safely, provide padding and move your pet away from stairs to prevent injury.
Treatment

Epilepsy can usually be managed with anti-convulsant drugs. If your veterinarian determines that your dog’s epilepsy is idiopathic, one or more of the following medications may be prescribed:

~ Phenobarbital helps reduce the frequency of your dog’s seizures and is the most prescribed medication for dogs with idiopathic epilepsy. It is generally a well-tolerated drug.

~ Potassium bromide is another seizure medication that may be added to your dog’s treatment, if she does not respond well to phenobarbital alone.
CBD ( Cannabidiol) as an alternative Treatment
For pets suffering from seizures, the use of Cannabidiol has been shown to be an effective, non-toxic form of treatment. Statistically speaking, a survey conducted by AHVMA that relied on pet-owner testimonials reported that between 61.8% and 95% of pet owners endorsed the benefits of treat products laced with CBD. According to another study titled, “Pharmacokinetics of cannabidiol in dogs,” researchers concluded that CBD has properties that can prevent convulsant and epileptic symptoms. 

Despite the studies and testimonials, it perhaps comes as no surprise that the use of CBD to treat pet health issues is being met with skepticism and concern. However, some of these concerns can perhaps be refuted when taking a closer look at CBD and where it comes from.

Though coming from the cannabis plant, CBD is the non-psychotropic hemp cultivar that is high in fiber and CBD, and low in THC. The latter (THC) actually has the potential to be harmful for pets. According to an article posted by Hawthorne Vet, the use of THC can bind to highly responsive receptors in a pet’s brain, leading to “static ataxia,” or behaviors that include the animal drooling, urinating excessively, and/or disorientation. Furthermore, if your pet is administered a product or drug that contains too much THC, there exists a risk for toxicity. Therefore, when considering the use of CBD on pets for health issues, it is important to avoid the use of THC and rather look for a product that contains only CBD, derived from hemp. 

When opting to utilize Cannabidiol to treat your pet’s seizures, it is important to start with the lowest dose possible and only then gradually increase the dosage, if necessary. Calculating the starting dose for your pet involves taking your pet’s weight in kilograms, determining the concentration of the CBD-product being used, and dividing the dosage across multiple administrations throughout the day. 

DOSES of CBD
In general, starting doses of CBD for pain and arthritis is 1 mg/10 lbs of body weight once to twice daily. I started my last dog on this dose to provided symptomatic pain relief for mouth cancer. I eventually increased his dose to 2 mg/10 lbs twice daily and he responded extremely well. 
So for pet seizures, we would be looking at a dose of  2 mg/10 lbs a day at the low end or 10 mg/10 lbs daily.
1. Talk to your vet! Your dog needs to stay on current ant-seizure meds and slowly wean off.
2. I would start for the 1st week on the low dose of 1 mg/10 lbs a day then increase to twice a day by the end of the week.
3. Then it’s a matter of lowering the conventional medications and seeing if the seizures are decreasing.
4. It may mean getting up to the higher doses of 2-5 mg/10 lbs a day.
Heal Your Pet At Home!

Best Wishes,

Dr Andrew Jones, DVM

*Please NOTE, Dr. Jones is not endorsing a specific CBD Hemp Product in this article.

CBD Hemp Oil Bulletproof Coffee! CBD Hemp Oil and Coconut Oil: How MCT Oil Acts as a Carrier for Cannabinoids.

CBD Hemp Oil Bulletproof Coffee

 

It seems like everyone these days is discussing the benefits of CBD Hemp Oil and looking for information about the best way to add this powerful supplement to their routines.

A common question people ask is in regards to the most efficient way to take CBD oil so that the cannabinoids in the oil have the easiest time interacting with the body. It is here that coconut oil and CBD oil’s relationship comes into focus.

Cannabinoids are fat soluble, meaning they break down and are stored in fat rather than water. Because of this trait, cannabinoids are most effective when consumed with fat, increasing their bioavailability. However, it appears that the type of fat matters.

Saturated fats are important carriers for cannabinoids to be absorbed into the body. Coconut oil contains saturated fat at levels close to 80%, giving cannabinoids the fat cells it needs to move through the body, encouraging faster processing and use by the endocannabinoid system.

Specifically, coconut oil contains medium-chain triglycerides or fatty acids. Using coconut oil or other products that contain medium-chain triglycerides (MCT oils) triggers a relatively rapid release of cannabinoids when compared to other oils because MCT oils are directly metabolized into energy by the liver. This means that your body can burn those fats and put them – and the cannabinoids they hold – to use right away.

First thing in the morning, I apply CBD Hemp Oil under my tongue. I hold the CBD Hemp Oil under my tongue, without swallowing for at least 30 seconds. Then I prepare my morning cup of hot coffee. However, my coffee is not a normal cup of coffee. I add 1 tablespoon of coconut MCT oil, 1 tablespoon of grass feed unsalted butter with just a little bit of coconut milk to the fresh brewed coffee, then stir it up until it is blended. I use an electric stir stick to blend all the ingredients together. Add any additional flavorings by sprinkling cinnamon, turmeric, or ginger on top. Then drink up… enjoy your delicious and healthy cup of coffee!

I call this my ‘CBD Bullet Proof Coffee’.  I don’t add the CBD oil into the coffee because it is more effective if you add it directly under your tongue so that it absorbs faster through the mucous membrane, instead of being absorbed through your digestive system. So absorb the CBD Hemp Oil first, then follow that with the bullet proof coffee. 

What a powerful way to start the day! 

~ Rev. Tiffany White Sage Woman

http://goldylocks.myCTFOcbd.com 

 

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